PERSONAL DE APOYO
RAGO MarÍa virginia
artículos
Título:
Isolation and characterization of an H9N2 influenza virus isolated in Argentina
Autor/es:
KEMIN XU; LUCAS FERRERI ; AGUSTINA RIMONDI ; VALERIA OLIVERA ; MARCELO ROMANO; HEBE FERREYRA ; M. VIRGINIA RAGO; MARCELA UHART ; HONGJUN CHEN ; TROY SUTTON ; ARIEL PEREDA
Revista:
VIRUS RESEARCH
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2012 vol. 168 p. 41 - 47
ISSN:
0168-1702
Resumen:
As part of our ongoing efforts on animal influenza surveillance in
Argentina, an H9N2 virus was isolated from a wild aquatic bird (Netta peposaca),
A/rosy-billed pochard/Argentina/CIP051-559/2007 (H9N2) herein
referred to as 559/H9N2. Due to the important role that H9N2 viruses
play in the ecology of influenza in nature, the 559/H9N2 isolate was
characterized molecularly and biologically. Phylogenetic analysis of the
HA gene revealed that the 559/H9N2 virus maintained an independent
evolutionary pathway and shared a sister-group relationship with North
American viruses, suggesting a common ancestor. The rest of the genome
segments clustered with viruses from South America. Experimental
inoculation of the 559/H9N2 in chickens and quail revealed efficient
replication and transmission only in quail. Our results add to the
notion of the unique evolutionary trend of avian influenza viruses in
South America. Our study increases our understanding of H9N2 viruses in
nature and emphasizes the importance of expanding animal influenza
surveillance efforts to better define the ecology of influenza viruses
at a global scale.