Characterization of the antiparasitic bephenium as an agonist of Caenorhabiditis elegans levamisole-sensitive nicotinic receptors

TURANI, O.; HERNANDO, G.; BOUZAT, C.

Montevideo

Otro; First Latin American Worm Meeting; 2017

We found that bephenium activates L-AChRs lacking LEV-8 although the activity pattern differs from that of wilt-type L-AChRs. Overall, we characterized the agonistic action of bephenium, which is used for parasitic infections caused by intestinal helminths, at the C. elegans L-AChR.