INVESTIGADORES
SARNACKI Sebastian Hernan
artículos
Título:
Host response to a dam mutant of Salmonella enterica serovar Enteritidis with a temperature-sensitive phenotype.
Autor/es:
GIACOMODONATO M.N.; SARNACKI S.H., CACCURI R.L.; CACCURI R.L; SORDELLI D.O.; CERQUETTI M.C.
Revista:
INFECTION AND IMMUNITY
Editorial:
AMER SOC MICROBIOLOGY
Referencias:
Año: 2004 vol. 72 p. 5498 - 5501
ISSN:
0019-9567
Resumen:
The temperature-sensitive dam mutant strain of Salmonella enterica serovar Enteritidis SD1 is highly attenuated and induces innate and protective immunity in mice. SD1 activates NF-kappaB and induces gamma interferon secretion. Early interaction of the SD1 mutant with intestinal epithelial cells was associated with ruffling of enterocytes. Invading bacteria were found inside Peyer´s patches after inoculation.
