INVESTIGADORES
MINARI Roque Javier
congresos y reuniones científicas
Título:
FILM-FORMING THERMORESPONSIVENANOGELS FOR DERMAL PROTEIN DELIVERY
Autor/es:
SONZOGNI, ANA S.; GONZALEZ, VERÓNICA D. G.; GUGLIOTTA, LUIS M.; MINARI, ROQUE J.
Lugar:
Punta Cana
Reunión:
Conferencia; Polymer Reaction Engineering X (PRE 10); 2018
Institución organizadora:
ECI
Resumen:
In this work a novel process was designed to synthesize thermoresponsive NGs with film-forming ability.This strategy pursues to synthesize N-vinylcaprolactam (VCL)-based nanogels with a separate phase composed of a random copolymer of VCL-butyl acrylate (BA)that promotes film formation by particle coalescence. The crosslinked poly(VCL) phase, which presents a transition temperature close to the body temperature (32-38°C), provides a reservoir to hold and transport drugs or biomacromolecules.
