INVESTIGADORES
ACOSTA patricio Leandro
congresos y reuniones científicas
Título:
Analysis of the Association between Specific Antibody Response against Respiratory Syncytial Virus Fusion Protein Conformations and Life-Threatening Infection in Previously Healthy Infants
Autor/es:
BONNIN F; TALARICO LB; PHUNG E; AZAD K; FEROLLA FM; BYRNE AB; ACOSTA PL; TOLEDANO A; CARATOZZOLO A; CONTRINI MM; GRAHAM BS; RUCKWARDT TJ; LOPEZ EL
Lugar:
Washington
Reunión:
Congreso; IDweek; 2022
Institución organizadora:
Infectious Diseases Society of America
Resumen:
Background. Specific humoral response against pre-fusion (pre-F) conformation of respiratory syncytial virus (RSV) F protein has been proposed to play a role against severe infection. We aimed to analyze the association between serum IgG titers against pre-F and post-fusion (post-F) conformations of RSV F protein and life-threatening RSV disease (LTD) in previously healthy infants.Methods. Prospective cohort study including previously healthy infants