INVESTIGADORES
CARACCIOLO pablo Christian
congresos y reuniones científicas
Título:
MESOPOROUS SILICA ELECTROSPUN MEMBRANES FOR BONE TISSUE ENGINEERING APPLICATIONS
Autor/es:
N.S. INCHAURRONDO; P.C. CARACCIOLO
Lugar:
Mar del Plata
Reunión:
Congreso; XII Latin-American Congress of Artificial Organs and Biomaterials (XII COLAOB); 2023
Institución organizadora:
INTEMA
Resumen:
Silica‐based materials exhibit biocompatibility and biodegradability, making themsuitable for long‐term support in tissue regeneration. In particular, mesoporous silica can also be consideredbioactive due to its large surface area that exposes a high density of reactive silanol functional groups [1].These groups facilitate a rapid release of soluble silicon in the form of silicic acid as a result of ion exchange inphysiological fluid. Moreover, this behavior enables the adsorption of glycoproteins, which in turn can enhancecell adhesion, proliferation, osteoblast expression, and mineralization [2]. Therefore, the aim of this study is toobtain a mesoporous nanostructured silica membrane with high specific surface area and fibrous morphologyfor potential use in bone tissue engineering applications.
