Synthesis of Water-Soluble Oligomers From Imidazole, Ethyleneglycol Diglycidyl Ether, and Methacrylic Acid. An Insight Into the Chemical Structure, Aggregation Behavior and Formation of Hollow Spheres

LOMBARDO LUPANO, LA; LÁZARO MARTÍNEZ, JM; VIZIOLI, NM; TORRES, DI; CAMPODALL'ORTO, V

MACROMOLECULAR MATERIALS AND ENGINEERING (PRINT)

WILEY-V C H VERLAG GMBH

Lugar: Weinheim; Año: 2015 vol. 301 p. 167 - 181

1438-7492

The synthesis of non-soluble polyampholytes was modified to obtain water-soluble oligomers, by a sequential reaction at 60 °C of imidazole (IM), ethyleneglycol diglycidyl ether (EGDE) and methacrylic acid (MAA). The hydrogel Poly(EGDE-IM) with disubstituted imidazole (IM+) residues, enhanced its solubility in water by functionalization with Poly(MAA). NMR and mass spectrometry evidenced ester groups, Poly(MAA) chains, Poly(EGDE), and IM+ links. Capillary electrophoresis evidenced populations with positive net charge at pH lower than 9, due to IM+ and protonatable residues (IMH+). Water-soluble aggregates of oligomers were detected by size exclusion chromatography. The product aggregated with cations such as Fe(II) adsorbing anionic compounds, and formed hollow spheres when citric acid was present.