IBCN 20355
INSTITUTO DE BIOLOGIA CELULAR Y NEUROCIENCIA "PROFESOR EDUARDO DE ROBERTIS"
Unidad Ejecutora - UE
artículos
Título:
Adenosine receptor changes throughout light induced retinal degeneration in the rat.
Autor/es:
EM. LÓPEZ; M. REY-FUNES; JJ. LÓPEZ-COSTA; IM. LARRAYOZ; M. SOLIÑO; N. MARTIGNONE; M. VACOTTO; E. GIRARDI; A. MARTÍNEZ
Revista:
NEUROSCIENCE LETTERS
Editorial:
ELSEVIER IRELAND LTD
Referencias:
Lugar: Ireland; Año: 2018 vol. 687 p. 259 - 267
ISSN:
0304-3940
Resumen:
ABSTRACT.The modulation of adenosine receptors, A1 (A1R) and A2A (A2AR), is neuroprotective in different models of retinal injury. In order to understand the processes underlying retinal degeneration, we studied the expression of adenosine receptors in the retinas of control and continuously illuminated (CI) rats by qRT-PCR, Western blot (WB) and immunohistochemistry (IHC). Significant increases of A1R, A2AR, and A2BR mRNAs at 1, 5, and 7 days of CI (P
