Effects of a high-fat diet on male fertility in high fertility performance mice

GIACCAGLI M; PATRICIA S. CUASNICÚ; RAINERO CACERES TS; DALTON N; COHEN DJ; GOMEZ ELIAS MD; DE SIERVI A; DA ROS VG

Congreso; XX Jornadas Anuales de la Sociedad Argentina de Biología; 2018

The metabolic syndrome (MeS) is defined as an increase in 3 of the followingfactors: visceral adiposity, triglycerides, cholesterol, fasting glucose andblood pressure. Considering the worldwide rise in the prevalence of thissyndrome during the last years, the aim of this study was to evaluate MeS effectson male fertility in mice with high reproductive performance. For this purpose,three-week-old male mice received a control diet (CD, 6% fat)or a high-fat diet (HFD, 30% fat) for 19 weeks. HFD mice ingested a higher amount of fat than CD mice (0.970.01 g of fat/day, n=9,