INVESTIGADORES
MUSUMECI Matias Alejandro
congresos y reuniones científicas
Título:
Molecular Basis for the high catalytic efficiency of plant FNRs
Autor/es:
MUSUMECI, M. A.; RIAL, D. V.; CATALANO DUPUY, D. L.; ARAKAKI, A. K.; CECCARELLI, E. A.
Lugar:
Rosario, Argentina.
Reunión:
Congreso; SAIB 42th Annual Meeting.; 2006
Institución organizadora:
Sociedad Argentina de Investigación Bioquímica y Biología Moleculat (SAIB)
Resumen:
FNRs are ubiquitous flavoenzymes that participate in a broad range of redox metabolic pathways. FNRs consist of two domains; one involved in the binding of the prosthetic group FAD Y308 - isoalloxazine interaction. Our results exemplify how the activity and high stability and show that in the FNR the volume of some aliphatic amino acids have been evolutively selected to maximize enzyme catalytic efficiency.