INVESTIGADORES
MINAHK Carlos Javier
artículos
Título:
Effect of Enterocin CRL35 on Listeria monocytogenes cell membrane
Autor/es:
MINAHK, C; FARIAS, M. E.; SESMA, F.; MORERO, R. D.
Revista:
FEMS MICROBIOLOGY LETTERS
Editorial:
Elsevier
Referencias:
Lugar: Amsterdam; Año: 2000 vol. 192 p. 79 - 83
ISSN:
0378-1097
Resumen:
The antimicrobial peptide Enterocin CRL35, a class II bacteriocin, produces at high concentrations (8 microg ml(-1)) localized holes in the wall and cellular membrane of Listeria monocytogenes, reflected in the efflux of macromolecules such as proteins and other ultraviolet-absorbing materials. At lower concentrations (0.5 microg ml(-1)), neither ultra structural changes nor macromolecules efflux were observed, however potassium and phosphate ions were released, dissipating the proton motive force. As a result the bacteria were killed.
