Modified resistogram methro for the study of yeast from oral mucosa of cancer and non-cancer patients with candidiasis ande healthy volenteers

BULACIO, L.; PUIGDOMENECH, G. ; SORTINO, M.; RAMOS, L.; LÓPEZ, C.; RAMADÁN, S.

Rosario

Congreso; XVI Congreso y XXXIV Reunión anual Sociedad Biología de Rosario; 2014

Genus Candida is part of microbiota in human skin and mucous membranes. However, it can cause opportunistic infections in immunocompromised patients, such as those under oncological treament. The ability to invade and antifungal resistance promote the development of infections. The aim of this study was to compare characteristics of Candida albicans strains, isolated from oral cavity in three study groups: cancer patients with radiotherapy in head and neck (N=31), non-cancer patients with candidiasis (N=48), and healthy volunteers (N=45). They were cultured in Sabouraud agar supplemented with sodium selenite (A), boric acid (B), cetrimide (C), sodium periodate (D), malachite green (F) and copper sulfate (G) (modified resistogram method). Growth in the different media was recorded, being for example [ABCDFG] an isolates resistant to all compounds, and [A----G], a resistant isolate to boric acid and copper sulphate. Frequence of C.albicans profiles were not the same in different groups (p