Synthesis, structure and antifungal properties of Co(II)–sulfathiazolate complexes

SEBASTIAN BELLU; ESTELA HURE; MARCELA TRAPE; CLAUDIA TROSSERO; GABRIEL MOLINA; CLAUDIA DROGO; PATRICIA A.M. WILLIAMS; ANA MARIA ATRIA; JUAN CARLOS MUÑOZ ACEVEDO; SUSANA ZACCHINO; MAXIMILANO SORTINO; DARÍO CAMPAGNOLI; MARCELA RIZZOTTO

POLYHEDRON

Elsevier Ltd

Lugar: Gainesville, Florida; Año: 2005 vol. 24 p. 501 - 509

0277-5387

The reaction between sulfathiazole and cobalt(II) leads to a pink solid, [CoII(ST)2(H2O)4] (1), which, after 7-10 days in the mother solution, transforms into red crystals of [CoII(ST)2(H2O)3]n (2) (ST = sulfathiazolate). The Co(II) ion exhibits an octahedral environment in both compounds. Differences between them were noted in the IR spectra in the region corresponding to signals of the amine group. Antifungal properties of (1) were evaluated, showing activity against both Aspergillus fumigatus (the same as the ligand) and Aspergillus flavus (better than the ligand).