INVESTIGADORES
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artículos
Título:
Computational fluid dynamic simulations of imaged-based stented coronary bifurcation models
Autor/es:
C. CHIASTRA; S. MORLACCHI; D. GALLO; U. MORBIDUCCI; R. CARDENES; I. LARRABIDE; F. MIGLIAVACCA
Revista:
JOURNAL OF THE ROYAL SOCIETY INTERFACE
Editorial:
ROYAL SOC
Referencias:
Lugar: Londres; Año: 2013 p. 1 - 13
ISSN:
1742-5689
Resumen:
One of the relevant phenomenon associated with in-stent restenosis
in coronary arteries is an altered haemodynamics in the stented region.
Computational fluid dynamics (CFD) offers the possibility to investigate
the haemodynamics at a level of detail not always accessible within
experimental techniques. CFD can quantify and correlate the local haemodynamics
structures which might lead to in-stent restenosis. The aim of
this work is to study the fluid dynamics of realistic stented coronary
artery models which replicate the complete clinical procedure of stent
implantation. Two cases of pathologic left anterior descending coronary
arteries with their bifurcations are reconstructed from computed tomography
angiography and conventional coronary angiography images. Results
of wall shear stress and relative residence time show that the wall regions
more prone to the risk of restenosis are located next to stent struts, to the
bifurcations and to the stent overlapping zone for both investigated
cases. Considering a bulk flow analysis, helical flow structures are generated
by the curvature of the zone upstream from the stent and by the
bifurcation regions. Helical recirculating microstructures are also visible
downstream from the stent struts. This study demonstrates the feasibility
to virtually investigate the haemodynamics of patient-specific coronary
bifurcation geometries.