KOCHEN Sara Silvia
The effect of unilateral low-frequency stimulation of hipocampal on seizure development induced by hipocampal kindling in rats
ANESSI C., FRANGELLA J., CABALLERO M., BARROSO M., KOCHEN S.
The present study was designed to investigate the effect of unilateral low-frequency stimulation (LFS) of hipocampal on seizure development induced by hipocampal kindling in rats, model of complex partial epilepsy. LFS-induced decrease in kindling rate was predominantly due to the animals in the LFS groups remaining longer in stages 03 (P<0.05). These findings may provide a new insight into establishing an effective and long-lasting therapy for seizure prone people.