INVESTIGADORES
KOCHEN Sara Silvia
artículos
Título:
Prognosis of epilepsy in a community-based
Autor/es:
KOCHEN S, MELCON MO.
Revista:
ACTA NEUROLOGICA SCANDINAVICA
Editorial:
Blackwell Munksgaard
Referencias:
Año: 2005 vol. 112 p. 370 - 374
ISSN:
0001-6314
Resumen:
Objective To assess the prognosis of epilepsy, the possibility of
achieving remission of seizures, in patients who were identified in a
population-based study carried out in Juný´ n, a city of about 70,000
inhabitants in Buenos Aires Province, Argentina. On January 1, 1991
(prevalence day), 106 people had epilepsy, including 64 (60%) with the
condition active. Methods Eight years later, we revisited the patients
identified in the prevalence study. We analyzed risk factors in relation
to remission of seizures. We also confirmed the specific cause of
death. Results Ninety-six patients were revisited (10 were completely
lost to follow-up). We divided them into two groups: the group in
terminal remission (defined as a seizure-free period that extended from
prevalence day until the visit day in 1998) which included 64 people
(66.7%), and the group of those who continued to have seizures which
included 32 (33.3%) patients, of whom eight (25%) died. The overall
standardized mortality ratio was 2.45; the rate was two and a half times
that of the general national population. Conclusion The better
prognosis was observed in the group with generalized idiopathic
epilepsy syndrome. Patients with epilepsy secondary to underlying
structural causes had the worst prognosis, with higher mortality.To assess the prognosis of epilepsy, the possibility of
achieving remission of seizures, in patients who were identified in a
population-based study carried out in Juný´ n, a city of about 70,000
inhabitants in Buenos Aires Province, Argentina. On January 1, 1991
(prevalence day), 106 people had epilepsy, including 64 (60%) with the
condition active. Methods Eight years later, we revisited the patients
identified in the prevalence study. We analyzed risk factors in relation
to remission of seizures. We also confirmed the specific cause of
death. Results Ninety-six patients were revisited (10 were completely
lost to follow-up). We divided them into two groups: the group in
terminal remission (defined as a seizure-free period that extended from
prevalence day until the visit day in 1998) which included 64 people
(66.7%), and the group of those who continued to have seizures which
included 32 (33.3%) patients, of whom eight (25%) died. The overall
standardized mortality ratio was 2.45; the rate was two and a half times
that of the general national population. Conclusion The better
prognosis was observed in the group with generalized idiopathic
epilepsy syndrome. Patients with epilepsy secondary to underlying
structural causes had the worst prognosis, with higher mortality.Methods Eight years later, we revisited the patients
identified in the prevalence study. We analyzed risk factors in relation
to remission of seizures. We also confirmed the specific cause of
death. Results Ninety-six patients were revisited (10 were completely
lost to follow-up). We divided them into two groups: the group in
terminal remission (defined as a seizure-free period that extended from
prevalence day until the visit day in 1998) which included 64 people
(66.7%), and the group of those who continued to have seizures which
included 32 (33.3%) patients, of whom eight (25%) died. The overall
standardized mortality ratio was 2.45; the rate was two and a half times
that of the general national population. Conclusion The better
prognosis was observed in the group with generalized idiopathic
epilepsy syndrome. Patients with epilepsy secondary to underlying
structural causes had the worst prognosis, with higher mortality.Results Ninety-six patients were revisited (10 were completely
lost to follow-up). We divided them into two groups: the group in
terminal remission (defined as a seizure-free period that extended from
prevalence day until the visit day in 1998) which included 64 people
(66.7%), and the group of those who continued to have seizures which
included 32 (33.3%) patients, of whom eight (25%) died. The overall
standardized mortality ratio was 2.45; the rate was two and a half times
that of the general national population. Conclusion The better
prognosis was observed in the group with generalized idiopathic
epilepsy syndrome. Patients with epilepsy secondary to underlying
structural causes had the worst prognosis, with higher mortality.Conclusion The better
prognosis was observed in the group with generalized idiopathic
epilepsy syndrome. Patients with epilepsy secondary to underlying
structural causes had the worst prognosis, with higher mortality.