Baccharis flabellata furane neo-clerodan diterpenes as NO and ROS scavenger

FUNES MD; TONN CE; KURINA SANZ MB

Cordoba

Congreso; 16th International Congress of Photobiology; 2014

Fac. Ciencias Químicas, Universidad Nacional de Córdoba ? INFIQC-CONICET

The furane neo-clerodan diterpene flavelloic acid (FNC) and its dimeric derivative (FNCD) have been detected in the aerial parts of Baccharis flabellata. Although interesting bioactivities, such as antifeedant and anti-inflammatory have been attributed to FNC, there is no information about the role of these compounds in plants exposed to UV-B stress conditions. We postulate that the natural photochemical dimerization take place under UV-B irradiation. Taking into account that reactive oxygen species (ROS) such as superoxide anion (O2.-) or hydrogen peroxide (H2O2) as well as nitric oxide (NO) act as mediators in responses to excessive UV-B radiation in different plant organelles we tested the scavenger capacity of FNC and FNCD in in- vitro assays. From our in-vitro results we can assume that FNCD as well FNC act as NO scavengers, being the dimmer more effective than the monomer. On the contrary, none of them showed specific ROS scavenger activity, when they were compared toward ascorbic acid.