INVESTIGADORES
GOROSTIZAGA Alejandra Beatriz
artículos
Título:
Tyrosine phosphatase in steroidogenis cells: regulation and fuction.
Autor/es:
ALEJANDRA GOROSTIZAGA; FABIANA CORNEJO MACIEL; LAURA BRION; PAULA MALOBERTI; ERNESTO J PODESTÁ; CRISTINA PAZ
Revista:
MOLECULAR AND CELLULAR ENDOCRINOLOGY.
Editorial:
North Holland Publishing
Referencias:
Lugar: Londres; Año: 2006
ISSN:
0303-7207
Resumen:
In adrenocortical and Leydig cells PKA activation by trophic hormones increases the activity ofprotein tyrosine phosphatases and also induces the expression of MAP kinase phosphatase 1 (MKP-1), a dualactivity protein phosphatase (serine/threonine and tyrosine). This work summarizes the knowledge on the regulation and the role played by cAMP-activated tyrosine phosphatases as well as MKP-1 in the hormonal activation of the acute and chronic phases of steroidogenesis.
