INVESTIGADORES
PEREZ MILLAN Maria Ines
artículos
Título:
Spastic ataxia with eye-of-the-tiger-like sign in 4 siblings due to novel compound heterozygous AFG3L2 mutation
Autor/es:
CALANDRA, CRISTIAN R.; BUDA, GUADALUPE; VISHNOPOLSKA, SEBASTIAN A.; OLIVERI, JAEN; OLIVIERI, FEDERICO A.; PÉREZ MILLÁN, MARÍA I.; BIAGIOLI, GERMAN; MIQUELINI, LUIS A.; PELLENE, ALEJANDRO L.; MARTI, MARCELO A.
Revista:
PARKINSONISM & RELATED DISORDERS
Editorial:
ELSEVIER SCI LTD
Referencias:
Año: 2020 vol. 73 p. 52 - 54
ISSN:
1353-8020
Resumen:
The eye-of-the-tiger (EOT) is a neuroradiologic sign observed on T2-weighted sequences that refers to a central high signal intensity in the anteromedial aspect of both globus pallidus (GP) and a surrounding low signal intensity due to excess iron deposition. Combining T2 and susceptibility-weighted images (SWI) allows an optimal characterization of iron accumulation. The EOT sign is considered almost pathognomonic of pantothenate kinase-associated neurodegeneration (PKAN)
