Zearalenone adsorbent based on a lyophilized indigenous bacterial Lactobacillus plantarum strain as feed additive for pigs: A preliminary study in vivo

RICCIO BELÉN; DIEGUEZ SUSANA N; GONZALEZ SILVIA NELINA; VEGA MARÍA FERNANDA; TAPIA MARÍA OFELIA

CURRENT MICROBIOLOGY

SPRINGER

Lugar: Berlin; Año: 2021 vol. 78 p. 1807 - 1812

0343-8651

Feed contamination with naturally occurring mycotoxins is an unavoidable condition of significant concern in intensive productions. The presence of zearalenone in the diet can cause major reproductive disorders, particularly in pigs. In order to reduce the consequences of intoxication, mycotoxin adsorbents are incorporated into feed. In the present study, zearalenone adsorption capacity of a lyophilized indigenous strain of Lactobacillus plantarum (L4; previously isolated from pig´s rectal swabs) was first evaluated in vitro. A preliminary study in vivo was then performed in which the indigenous Lactobacillus plantarum strain was lyophilized and the powder obtained (L-L4) was incorporated into the diet of gilts (2 gilts received basal diet (control) and 2 received basal diet containing 2g/Kg L-L4 (treated)). After an adaptation period, all the feed was contaminated with zearalenone at a dose of 0.93 mg ZEA/Kg. Results from a test in vitro assay of the powder showed that L-L4 adsorbed 87.9 % (SD 3.97) of zearalenone in 0.9% NaCl solution. In the in vivo exploratory study, a higher daily weight gain and lower vulva area were observed in gilts that incorporated L-L4 to the diet. Additionally, higher zearalenone concentrations were eliminated in the faeces from treated animals. The use of a product based on a lyophilized indigenous Lactobacillus strain to protect gilts from detrimental effects of zearalenone consumption has shown promising results so far. However, further studies are required in order to accurately assess its impact and evaluate doses according to different degrees of mycotoxins contamination