INVESTIGADORES
TUEROS Matias Jorge
artículos
Título:
Assessment of mutagenicity and toxicity of different-size fractions of air particulates from La Plata, Argentina, and Leipzig, Germany
Autor/es:
L. MASSOLO; A. MULLER; M.J. TUEROS; M. REHWAGEN; U. FRANNK; A. RONCO; O. HERBARTH
Revista:
ENVIRONMENTAL TOXICOLOGY
Editorial:
JOHN WILEY & SONS INC
Referencias:
Año: 2002 vol. 17 p. 219 - 231
ISSN:
1520-4081
Resumen:
Airborne particulates, especially fine particles and bound chemical compounds, are a potential mediator of adverse health effects. In this study an analysis was done of the concentration and size distribution of air particulate matter, the content of bound polycyclic aromatic hydrocarbons (PAHs), and the biological effects of organic extracts from different fractions of dust that had been influenced by urban and industrial emissions from the regions of La Plata, Argentina, and Leipzig, Germany, along with samples from control areas. Air particulate matter was sampled in summer and winter in each region using a high-volume sampler with a six-stage cascade impactor, classifying dust in six size fractions from 10-mm particles to those less than 0.49 mm in size. Organic extracts of dust were tested for mutagenicity (Ames test, Salmonella typhimurium TA98 strain, S9+) and cytotoxicity (Tetrahymena pyriformis test system, growth rate, cell respiration). The content of PAHs was analyzed by high-performance liquid chromatography (HPLC) with diode array and fluorescence detection. Mutagenic and cytotoxic effects were found to be associated with very fine (m0.49 mm) and fine (
