INVESTIGADORES
DE LA MATA Manuel
artículos
Título:
Turning the table on miRNAs
Autor/es:
DE LA MATA, MANUEL; GROßHANS, HELGE
Revista:
Nature Structural and Molecular Biology
Editorial:
Nature Publishing Group
Referencias:
Año: 2018 vol. 25 p. 195 - 197
ISSN:
1545-9993
Resumen:
Transcripts with highly complementary sequences can target microRNAs (miRNAs) for degradation, but the physiological relevance of target-directed miRNA degradation (TDMD) has remained unclear. Bitetti et al. now identify a conserved vertebrate RNA that induces TDMD in the cerebellum of zebrafish and mouse to promote wild-type animal behaviors.
