NEUROPHYSIOLOGICAL MARKERS AFTER MEMORY REACTIVATION THE LASTING FOOTPRINTS OF THE RECONSOLIDATION PROCESS

CAMPASSI LIBERTAD; EUGENIO RODRIGUEZ; GERMAN CAMPOS ARTEAGA; M.E. PEDREIRA; LUZ BAVASSI

Buenos Aires

Congreso; XXXV Congreso SAN 2020; 2020

SAN

The process of reconsolidation is fundamental in daily life, it is responsible for updating both the strength and the content of a consolidated memory. Reconsolidation occurs when original information is reactivated by the presentation of specific reminders that trigger memory labilization followed by a re-stabilization phase. In a previous study, we showed that the retrieval of memories that had gone through the reconsolidation process involved a more extensive and with a higher clustering coefficient neural network than memories that had been re-exposed to the original context. These results raise new questions about how and when these lasting changes are printed in the brain. In this work, with an EEG of 64 channels, we explored to characterize the dynamic changes that occur in the brain network during the strengthening of a declarative memory . In this line, we analyzed the neurophysiological markers at a resting state immediately after the presentation of a reminder that triggers reconsolidation and another that does not. We found differences between both neural correlates. The resting after the presentation of the reminder that triggers reconsolidation had a higher amplitude of low frequencies (less than 4Hz) in the left central-parietal zone and a decreased in the right frontal region. These results might be the lasting footprints that reconsolidation prints in the brain."