INVESTIGADORES
RADIVOY gabriel Eduardo
artículos
Título:
Copper Nanoparticles Supported on Zinc Oxide as Efficient Catalyst for the N-Arylation of (Hetero)cyclic and Acyclic Amides
Autor/es:
Y. MOGLIE; E. MASCARĂ“; F. C. ZACCONI; G. RADIVOY
Revista:
CHEMISTRYSELECT
Editorial:
Wiley-VCH
Referencias:
Lugar: Weinheim; Año: 2021 vol. 6 p. 4412 - 4417
ISSN:
2365-6549
Resumen:
Copper nanoparticles (CuNPs) supported on ZnO are a highly active and selective heterogeneous catalyst for the N-arylation of cyclic and acyclic amides (Golberg coupling). The reaction conditions are mild, featuring K3PO4 as a base and N,N?-dimethylethylendiamine (DMEDA) as a ligand in refluxing acetonitrile. The CuNPs/ZnO catalyst can be recovered and reused in six cycles with only little loss of activity. The methodology can be successfully scaled up to gram scale without decreasing the catalytic activity.