Genes regulating the growth of myotomal muscle in teleost fish

JOHNSTON, IAN ALISTAIR; HALL, TOM; FERNÁNDEZ, DANIEL ALFREDO

Aquatic Genomics

Año: 2003; p. 153 - 166

Postembryonic muscle growth in fish differs from that in mammals inthat new muscle fibres continue to be produced throughout much of the life cycle.Growth involves the proliferation of a population of myogenic progenitor cellsshowing varying degrees of commitment to terminal differentiation. Muscle fibrerecruitment and hypertrophy are independently regulated during growth by a widerange of extrinsic (temperature, photoperiod, feeding regime) and intrinsic factors(genotype, sexual maturation state). In some species egg incubation temperaturehas long lasting effects on the number of muscle fibres recruited duringsubsequent stages of the life cycle. This suggests that the commitment of themyogenic progenitor cells destined to participate in fibre recruitment andhypertrophy is decided relatively early in development. Current knowledge aboutthe structure and function of genes regulating postembryonic muscle growth inteleosts is reviewed.