INVESTIGADORES
ESTRIN Dario Ariel
artículos
Título:
A Unique Family of Stable and Water-Soluble S-Nitrosothiol Complexes
Autor/es:
L.L. PERISSINOTTI; G. LEITUS; L. SHIMON; D.A. ESTRIN; F. DOCTOROVICH
Revista:
INORGANIC CHEMISTRY
Editorial:
American Chemical Society
Referencias:
Lugar: Columbus, OH; Año: 2008 vol. 47 p. 4723 - 4733
ISSN:
0020-1669
Resumen:
In this work, we present a complete and detailed experimental characterization and theoretical study of a varietyof coordinated S-nitrosothiols (RSNOs), such as cysteine derivatives, mercaptosuccinic acid, benzyl thiol, and phenylthiol. Some of them are extremely unstable and sensitive in free form. Strikingly, in contrast with free S-nitrosothiols,we found that, upon coordination to iridium, they become very stable even in aqueous solutions. The study ofthese coordinated complexes provides further insight on the elucidation of structural aspects dealing with the natureof the S-N bond in RSNOs, a fact which still remains a matter of controversy.
