Discovery of endogenous nitroxyl as a new redox player in Arabidopsis thaliana

ARASIMOWICZ-JELONEK, M.; FLORYSZAK-WIECZOREK, J.; SUAREZ, S.; DOCTOROVICH, F.; SOBIESZCZUK-NOWICKA, E.; BRUCE KING, S.; MILCZAREK, G.; R?BI?, T.; GAJEWSKA, J.; JAGODZIK, P.; ?YWICKI, M.

Nature Plants

Nature Research

Lugar: Londres; Año: 2023 vol. 9 p. 36 - 44

Nitroxyl (HNO) is the one-electron reduced and protonated congener of nitric oxide (•NO), owning a distinct chemical profile. Based on real-time detection, we demonstrate that HNO is endogenously formed in Arabidopsis. Senescence and hypoxia induce shifts in the redox balance, triggering HNO decay or formation mediated by non-enzymatic •NO/HNO interconversion with cellular reductants. The stimuli-dependent HNO generation supports or competes with •NO signalling, depending on the local redox environment.