Water State In Confined Regions Of Lipids Bilayers Observed By FTIR Spectroscopy

ANIBAL EDGARDO DISALVO; FRIAS, M DE LOS ANGELES

Sendai

Conferencia; 14th International Association of Colloid and Interface Scientists, Conference. (IACIS); 2012

Association of Colloid and Interface Scientists

The presence of water pockets or defects in lipid bilayers may explain the insertion of charged and polar peptides and aminoacids. The properties of these confined regions of water have not yet been analyzed.FTIR spectroscopy provides visualization at molecular level of the order-disorder increase due to the trans-gauche isomers in the lipid acyl chains. It is assumed that the increase of conformational isomers enhances water penetration beyond the polar head group region. In this condition, water may be present in different states according to the hydrophobic hydrophilic character of the wall it is facing.FTIR spectroscopy gives directly changes in water states following the bands at 3600 cm-1 parallel to the changes in the CH2 region. In this work we analyze the different water populations occurring below and above the phase transition of phosphatidylcholines and phosphatidylethanolamines of similar chain lengths.