ANTIBACTERIAL ACTIVITY OF TWO PLANT SPECIES COLLECTED FROM HUACA HUASI, TUCUMAN, ARGENTINA

SOLÓRZANO R.E, ZAMPINI, I.C., CUELLO S., ORDOÑEZ R.M., ISLA M.I..; ZAMPINI I.C; CUELLO A. S.; ORDOÑEZ R; ISLA M. I.

Jornada; XXIV Jornada científica de la asociacion de bioligia de Tucumán; 2007

In the last few years multiresistant strains to commercial antibiotics havee appeared in Argentina. Considerable attention has been devoted to natural products such as medicinal plants with antibacterial properties. The present study was conducted to investigate the antimicrobial activity of Tetraglochin cristatum and Chiliotrichiopsis keidelii against multiresistant Gram-negative and Gram-positive bacteria isolated from clinical samples obtained from a hospital in San Miguel de Tucumán. The plant material was collected at 1500 m above sea level in Tucumán, Argentina and macerated in ethanol 80º for 7 days at room temperature. Minimum inhibitory concentration (MIC) was determined by agar macrodilution assays. The MIC values were 300 to 1200 μg/mL. The Chiliotrichiopsis keidelii extract showed greater antibacterial activity against Gram-negative bacteria and Tetraglochin cristatum extract showed greater activity antibacterial against Gram-positive bacteria. In previous works we demonstrated that these phytotherapeutic agentsc also present activity as free radical scavengeers. Consequently, these tinctures could be used as antibiotics for topical use.