Coloquio

CIAPPONI A,; ARIEL BARDACH

Congreso; 23rd Cochrane Colloquium; 2015

Background: PROSPERO is an international open accesselectronic database of prospectively registered systematicreviews in health and social care. A unique registration numberand key features from the review protocol are recordedpermanently in order to avoid unplanned duplicationand enable comparison of reported review methods withwhat was planned in the protocol. Objectives: Toassess the progress of PROSPERO registering systematicreviews, in absolute terms and in relative terms comparedto systematic reviews published in MEDLINE. Methods:First, we identified the monthly cumulative registrationsand the status of these registrations on PROSPERO(http://www.crd.york.ac.uk/PROSPERO/) from inception date(22 February 2011). Second, we identified the annualpublications of systematic reviews in PubMed usingthe most specific filter developed by Montori et al.(((MEDLINE [tiab]) OR systematic[tiab])) AND ((review[tiab])OR meta-analysis[Publication Type]) and we also identifiedPROSPERO registrations (((prospero) AND ((registr* or crd)))).Results: From inception to 28 February 2015 (four years)6026 registrations were recorded in PROSPERO, most of them(87%) reporting an ongoing status (Table 1). We observedan increasing trend in the number of records (Figure 1). Theproportion of systematic reviews published in MEDLINE thatreported a CRD record number is also growing but, remainsbelow 2% (Figure 2). Conclusions: PROSPERO registration isgrowing but is still remarkably low. Hopefully the PRIMA-P2015 statement will boost this trend further.