BECAS
ROSALES HURTADO Juan JosÉ
artículos
Título:
Distinctive features of bovine alphaherpesvirus types 1 and 5 and the virus-host interactions that might influence clinical outcomes
Autor/es:
MARIN, MAIA; BURUCÚA, MERCEDES; RENSETTI, DANIEL; ROSALES, JUAN JOSÉ; ODEÓN, ANSELMO; PÉREZ, SANDRA
Revista:
ARCHIVES OF VIROLOGY
Editorial:
SPRINGER WIEN
Referencias:
Año: 2019 vol. 165 p. 285 - 301
ISSN:
0304-8608
Resumen:
Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they difer in their neuropathogenic potential. This review summarizes the fndings on the specifc mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation to respiratory and neurological syndromes, which characterize BoHV-1 and BoHV-5 infections, respectively.
