PRELIMINARY EVALUATION OF ALLOGRAFT FROM DECELLULARIZED CADAVERIC FASCIA LATA

CAROLINA LACERRA; ROMINA COMÍN; MARIANA PAULA CID; DIEGO MAURO SCHMETS; JULIO CESAR MATHIEU; TRISTAN LOPEZ LOZANO; CECILIA BEATRIZ SOBRERO; NANCY ALICIA SALVATIERRA

Revista Argentina de Bioingenieria

OJS/PKP

Año: 2020

2591-376x

The allograft from fascia lata has reconstructive capacity. It allows revascularization since the surrounding vesselsof the receiving scaffold and induces migration, proliferation and adhesion of the cellular components of granulation tissue forintegration to receiving tissue. Fascia lata grafts are used in various medical branches (traumatology and orthopedics,neurosurgery, ophthalmology, urogynecology and aesthetic medicine). These grafts are obtained by different processes and arepreserved by different methods according to the manufacturer. The aim of this work was to obtain, at the Tissue Bank inLaboratorio de Hemoderivados de la Universidad Nacional de Córdoba, an allograft from decellularized cadaveric human fascialata (freeze dried) and to evaluate cytotoxicity, microstructure and collagen content. The results showed that through obtainingand processing methods used here, we obtained an allograft with its histological structure preserved and no evidence ofcytotoxicity. Likewise, collagen content was not affected by decellularizing procedure