Mortality effects of semi-synthetic diterpenes on Tenebrio molitor

RETA, G. F.; GATICA, A.; SOSA, M. E.; TONN, C. E.; DONADEL O. J.

San Juan

Simposio; Second joint meeting of the biology societies from Argentina; 2011

Natural products (NP) have extensive structural and functional diversity and provide research topics for chemists, biologists and doctors. The use of synthetic pesticides for controlling insects has caused resistance, emergence of new pests, pollution and other damage resulting from accidental misuse and application. The NP of plants may be an option for an integrated management program and emerge as an alternative for controlling stored grain pests. Previously we report the insect growth regulatory effects of natural labdanes from Grindelia pulchella Dunal var. pulchella, in this study we obtained 12 semi-synthetic derivates of the natural metabolites and we show the effects they produced on adults of Tenebrio molitor. The mortality of larvae of T. molitor was studied by toxicity tests by topical application of the compounds and they were monitored every 24 hours until day 5, showing mortality values between 45 and 100%. The best results against insects were obtained with side chain oxygenated products. Acknowledgements: This work was supported by CONICET (PIP0628), ANPCyT (PICT-UNSL 2008-0022) UNSL (PROICO- 7301) and AECI (PCI A / 025750/09). 262.