Biochemical parameters in pleural fluids: new contributions in the etiologic diagnosis of body fluids.

ANABELA ANGELERI; ADRIANA ROCHER; BEATRIZ CARACCIOLO; MARCELA PANDOLFO; LUIS PALAORO; BEATRIZ PERAZZI.

British Jounal of Medicine and Medical Research

Science Domain International

Año: 2016 vol. 13 p. 1 - 9

Objectives: The aim of this study was to evaluate the usefulness of different cutoffs applied to thecellularity and various biochemical parameters (BP) (metabolic and enzymatic) to contribute to theetiologic diagnosis of pleural fluids (PF).Design and Methods: We studied 150 samples from patients with pleural effusion, admitted to theClinical Hospital. The cell count was total/mm3 (TCC) and differential. The simultaneousdetermination in pleural fluid (PF) and serum (S) of BP were performed on Roche Hitachi 917autoanalyzer: Glucose (GLU), protein (PT), albumin (ALB), cholesterol (COL), triglycerides (TG),lactate dehydrogenase (LDH), creatine kinase (CK), alanine aminotransferase (ALT), aspartateaminotransferase (AST), alkaline phosphatase (FAL), amylase (AMI), total bilirubin (BT). Statistical methods were c² and Fisher. A value of p 0.5 mg / dl would be also suitable fordifferentiating T and E, and to a lesser extent PF / S for CK, AMI and SAAG. GLU value < 60 mg /dl showed no utility except in empyema. ALP, AST and ALT did not allow differentiating exudatesfrom transudates.Conclusions: The use of a new cutoff for the TCC ≥ 500 cells / mm3 in the differential diagnosis ofPF is suggested. Different BP contributed to the differentiation between E and T.