Decidual vascularization in organogenesis after perigestational alcohol ingestion

ARGANDOÑA F; VENTUREIRA, MR; CEBRAL E; PALOMINO WA; SOBARZO C; BARBEITO C

REPRODUCTION

BIOSCIENTIFICA LTD

Lugar: Bristol; Año: 2019 vol. 158 p. 109 - 122

1470-1626

We hypothesized that perigestational moderate alcohol consumption in mouse produces abnormal mesometrial decidual angiogenesis-vascularization via altered expression of the VEGF/receptor system. CF-1 female mice were administered with 10% ethanol in drinking water for 17 days prior to and up to day 10 of gestation. Control females received water without ethanol. Treated females had reduced frequency of implantation sites with expanded vascular lumen (p