Association between inflammatory diet index, obesity and breast cancer in Córdoba, Argentina.

CABALLERO, VICTOR; NICLIS, CAMILA.; MUÑOZ, SONIA EDITH; GONZALEZ, MARÍA FLORENCIA; TUMAS, NATALIA; DÍAZ, MARÍA DEL PILAR; BECARIA COQUET, JULIA; CAMISASSO, MARÍA CECILIA; ROMÁN, MARÍA DOLORES; ABALLAY, LAURA.

Buenos Aires

Congreso; IUNS 21st International Congress of Nutrition; 2017

International Union of Nutritional Sciences

Background and objectives: Breast cancer (BC) is a multi¬factorial disease; several environmental factors have been linked to this pathology. Specifically, obesity and inflammatory diet have been associated with an increased risk of BC in women. Endocrine changes related to these factors trigger an inflammatory response, which favors the occurrence of BC. The aim of this research was to assess the association between the consumption of an inflam¬matory diet and BC risk, taking into account nutritional status, in Córdoba province (Argentina). Methods: A case-control study was conducted during 2008- 2016 period (346 cases of BC and 566 controls). An inflammatory diet score was developed including 15 dietary variables (nutrients and food groups consumption), obtained through a validated FFQ. A score (0, 0.5 or 1) was assigned for each variable included in the score depending on the compliance of dietary recommen¬dations. A higher score indicated a higher degree of adherence to an inflammatory diet. For each woman an inflammatory score was calculated. A multiple logistic regression model was performed to assess the association between BC occurrence and inflammatory diet, stratifying by nutritional status. Results: The inflammatory diet score mean was 6.7 (0.9) in all women included in the study. 20% of the women studied were obese. An increased risk of BC of 42% was observed for each unit of increased in the inflammatory diet score in this group (Odds Ratio: 1.42; Confidence Interval: 1.1-1.84). Conclusions: Obese women with an inflammatory diet have a greater risk of BC in Córdoba (Argentina).