INICSA 23916
INSTITUTO DE INVESTIGACIONES EN CIENCIAS DE LA SALUD
Unidad Ejecutora - UE
artículos
Título:
Analysis of mitochondrial enzymatic activity in blood lymphomonocyte fractions during infection with different trypanosoma cruzi strains
Autor/es:
LO PRESTI, MARÍA S.; VELÁZQUEZ LÓPEZ, DANIELA A.; PAGLINI-OLIVA, PATRICIA A.; BAZÁN, PAOLA C.; MILER, NOEMÍ; BÁEZ, ALEJANDRA L.; STRAUSS, MARIANA; RIVAROLA, HÉCTOR W.
Revista:
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SãO PAULO
Editorial:
INST MEDICINA TROPICAL SAO PAULO
Referencias:
Lugar: São Paulo; Año: 2020 vol. 62 p. 1 - 6
ISSN:
0036-4665
Resumen:
Proinflammatory and inflammatory mediators induced by Trypanosoma cruzi infectionincrease the oxidative stress, generating toxicity for cells targeting mitochondria of differenttissues. We studied the activity of citrate synthase and complexes I-IV of respiratory chainin mitochondria of blood lymphomonocyte fraction, from albino Swiss mice infectedwith different isolates of T. cruzi, during Chagas disease evolution. Complexes I-IV weremodified in infected groups (p
