PRELIMINARY EVALUATION OF ALLOGRAFT FROM DECELLULARIZED CADAVERIC FASCIA LATA

CAROLINA LACERRA; ROMINA COMÍN; MARIANA CID; DIEGO MAURO SCHMETS ; JULIO CESAR MATHIEU; TRISTAN LOPEZ LOZANO; CECILIA BEATRIZ SOBRERO; NANCY A. SALVATIERRA

piriapolis

Simposio; Congreso de Bioingeniería y Jornadas de Ingeniería Clínica 2020; 2020

The allograft from fascia lata has reconstructive capacity. It allows revascularization since the surroundingvessels of the receiving scaffold and induces migration, proliferation and adhesion of the cellular components ofgranulation tissue for integration to receiving tissue. Fascia lata grafts are used in various medical branches(traumatology and orthopedics, neurosurgery, ophthalmology, urogynecology and aesthetic medicine). These grafts areobtained by different processes and are preserved by different methods according to the manufacturer. The aim of thiswork was to obtain, at the Tissue Bank in Laboratorio de Hemoderivados de la Universidad Nacional de Córdoba, anallograft from decellularized cadaveric human fascia lata (freeze dried) and to evaluate cytotoxicity, microstructure andcollagen content. The results showed that through obtaining and processing methods used here, we obtained anallograft with its histological structure preserved and no evidence of cytotoxicity. Likewise, collagen content was notaffected by decellularizing procedure.