INVESTIGADORES
LUQUET carlos Marcelo
artículos
Título:
Oxidative effects and toxin bioaccumulation after dietary microcystin intoxication in the hepatopancreas of the crab Neohelice (Chasmagnathus) granulata
Autor/es:
SABATINI, S.E.; BRENA, B.; PIREZ, M.; RÍOS DE MOLINA, MC.; LUQUET C.M
Revista:
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Editorial:
ACADEMIC PRESS INC ELSEVIER SCIENCE
Referencias:
Lugar: Amsterdam; Año: 2015 vol. 120 p. 136 - 141
ISSN:
0147-6513
Resumen:
We studied the accumulation and depuration of microcystin-LR (MCLR) in the hepatopancreas of the crab Neohelice granulata fed twice weekly with either non toxic or MCLR-producing Microcystis aeruginosa (strain NPDC1 or NPJB, respectively) during seven weeks. We also analyzed MCLR effects on the oxidative stress- and detoxification-related variables, superoxide dismutase and glutathione-S-transferase activities, and the levels of reduced glutathione and lipid peroxidation (as thiobarbituric acid reactive substances, TBARS). Hepatopancreas MCLR content slightly increased during the first three weeks, up to 8.8171.84 ng g-1 wet tissue mass (WTM) and then started to decrease to a minimum of 1.5770.74 ng g-1 WTM at the seventh week (p