INVESTIGADORES
MARTINEZ PERALTA Liliana A.
artículos
Título:
Properties of Lymphocytic Choriomeningitis Virus Interfering particles
Autor/es:
L. MARTÍNEZ PERALTA, F. LEHMANN-GRUBE.
Revista:
ARCHIVES OF VIROLOGY
Editorial:
Springer Verlag.
Referencias:
Lugar: Viena, Austria.; Año: 1983 vol. 77 p. 61 - 69
ISSN:
0304-8608
Resumen:
Lymphocytic choriomeningitis virus (LCM virus) interfering particles (IP) were generated in cultivated cells and their properties determined. Unlike true defective interfering (DI) particles, LCM virus IP did not show the phenomenon of enrichment and, consequently, passaging the virus undiluted did not result in their accumulation; in fact, more IP were produced during dilute passages. Furthermore, the progeny of each of 20 plaques contained high numbers of IP. On the basis of these and previous observations, we consider LCM virus IP not deletion mutants but by-products of virus synthesis.
