Repellent activity of essential oils from species of San Juan, Argentina against nymphs of Triatoma infestans

LÓPEZ SB; ZYGADLO JA; ARAGÓN LM; FERESIN GE; TAPIA A; LÓPEZ ML

Mendoza, Argentina

Congreso; XXVIII Congreso Anual de la Sociedad de Biología de Cuyo; 2010

Sociedad Biología de Cuyo

Chagas disease is a major public health concern in Argentina with estimates near three millions infected people. Essential oils from (EO) Acantholippia seriphioides, Artemisia mendozana, Baccharis grisebachii, Lippia integrifolia, Satureja parvifolia and Tagetes mendocina were assayed in vitro for their repellence activity against five instar nymphs of T. infestans Chagas disease vector. Fresh aerial parts were hydrodistilled to obtain the EO in a Clevenger type apparatus. EO were evaluated at 1, 24 and 72 hours of treatment. Chemical composition was carried out by GC-MS. Percent Repellency (PR) was determined according to standard method. Two of seven EO were found to be class V and three were Class IV. On the basis of the percentage of repellency throughout the 72 h of treatment, the most repellent were B. grisebachii ( 92% PR), and L. integrifolia (86% PR) EOs. The good repellent activity of B. grisebachii , L. integrifolia. EO, provide evidence that these Andean species could be new potential source to alleviate local problems of Chagas´s disease. Acknowledgements: To Serv, Nac. Chagas, Cba., for providing T. infestans nymphs and CICITCA-UNSJ (I905), ANPCyT (PICT ´07- 01468) and CONICET (PIP´08 0407).