INVESTIGADORES
ABRAHAM gustavo Abel
congresos y reuniones científicas
Título:
Micro/nanofiber polyurethane scaffolds with functional properties
Autor/es:
F. MONTINI BALLARÍN; F. BUFFA; G.A. ABRAHAM
Lugar:
Los Cocos, Córdoba, Argentina
Reunión:
Simposio; V Simposio Chileno-Argentino de Polímeros, ARCHIPOL; 2009
Institución organizadora:
Universidad Nacional de Córdoba
Resumen:
Tissue
engineering and regenerative medice aim to develop biological
substitutes that restore, maintain or, improve the damaged tissue and
the organs functionality. The advances in nanotechnology in the last
years can solve some of the many issues related to the problems of the
traditional implants (Zhang and Webster, 2009). The nanofibrous
polymeric scaffolds have biomimetic features and can create an
extracellular matrix architecture in a nanoscale way. This morphologic
characteristic favors and stimulates the expression of specific signals,
and in combination with grown factors, proteins and therapeutic agents
have an important influence in the in vitro and in vivo cellular activity (Mikhalovsky et al.,
2004). Among the techniques available for preparing nanofibrous
scaffolds, electrospinning is the most versatile and attractive and
offers the possibility to manipulate and control the surface area, fiber
diameter, porosity, and pore size (Lannutti et al., 2007; Venugopal et al.,
2005). Recognizing the importance of electrical and mechanical
properties for several tissue reconstruction, conductive nanofibrous
scaffolds are interesting matrices for tissue engineering and
biotechnological applications.
In
this work, we present the preparation and characterization of
polyurethane nanocomposites scaffolds by electrospinning. The studied
parameters showed an influence in the macro and micromorphology of the
prepared systems. The addition of nanoparticles (carbon nanotubes)
allowed the preparation of nanocomposites with morphological and
functional features. The obtained nanofibrous scaffolds results of
interest for applications in biomedics devices and tissue engineering.