INVESTIGADORES
ABRAHAM gustavo Abel
congresos y reuniones científicas
Título:
Electrospinning of amoxicillin-loaded biodegradable polycaprolactone/hydroxyapatite nanofibers
Autor/es:
G. FURTOS; G. RIVERO; G.A. ABRAHAM
Lugar:
Novi Sad
Reunión:
Workshop; Meeting and Workshop on "Composite, nanofabrication, food and pharma related application and packaging, controlled release"; 2015
Institución organizadora:
University of Novi Sad y COST Action MP1206
Resumen:
In this work, porous matrices composed of PCL and nHAp loaded with amoxicillin (AMX) were prepared as material designed for biomedical applications. Different electrospun antibiotic-loaded nanocomposites were obtained by varying AMOX/nHAp ratio, to produce a series of PCL/AMOX, PCL/nHAp and PCL/AMOX/nHAp matrices.The structural, morphological, surface and thermal properties were characterized by using X-ray diffraction (XRD), scanning electron microscopy (SEM, EDAX), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and contact angle measurements. The results reveal that these electrospun nanocomposite amoxicillin-loaded scaffolds could be a promising biodegradable material for biomedical application. Antimicrobial testing is under progress.