INVESTIGADORES
ABRAHAM gustavo Abel
congresos y reuniones científicas
Título:
Characterization and properties of PCL / PDIPF matrices for biomedical applications
Autor/es:
J.M. FERNÁNDEZ; S.M. CORTIZO; A.M. CORTIZO; G.A. ABRAHAM
Lugar:
Granada, España
Reunión:
Congreso; European Polymer Congress EPF 2011, XII Congress of the Specialized Group of Polymers GEP; 2011
Institución organizadora:
European Polymer Federation
Resumen:
Currently there is a high interest in the study of synthetic biodegradable polymers for use as biocompatible scaffolds in different areas of tissue engineering and regenerative medicine. Poly(epsilon-caprolactone) (PCL) and poly(diisopropilfumarato) (PDIPF) have proven to be good substrates for adhesion, growth and differentiation of two osteoblastic cell lines, mouse calvaria derived MC3T3E1 and rat osteosarcoma UMR106, suggesting that these polymers can be useful in bone tissue regeneration. A blend material with better mechanical properties, intermediate degradation rate between the two homopolymers and demostrated biocompatibility was prepared and compatibilized by high intensity ultrasound starting from PCL and PDIPF. The aim of this study was to characterize and to evaluate the activity of MC3T3E1 cells compared to porous and non porous matrices of PCL/PFIP compatibilized.
