INVESTIGADORES
ABRAHAM gustavo Abel
congresos y reuniones científicas
Título:
Co-electrospinning of bioglass-loaded PCL nanofibers and amoxicillin-loaded Eudragit EPO nanofibers as coatings for metallic implants
Autor/es:
D. HEREDIA; E. GONZÁLEZ; A. DURANTINI; S. MARTINEZ ; G.A. ABRAHAM
Lugar:
Mar del Plata
Reunión:
Congreso; XII Latin-American Congress of Artificial Organs and Biomaterials (COLAOB 2023); 2023
Institución organizadora:
INTEMA (UNMdP-CONICET)
Resumen:
The use of metallic bone implants requires surface modification to improve thematerial properties, e.g., by using composite polymeric coatings. Electrospinning technique is highlyrecommended because the nanofiber structure mimics the extracellular matrix. Poly(ε-caprolactone) (PCL) is biocompatible and biodegradable, and bioglass (BG) can be included in the fibers providing osteogenesis and angiogenesis features. Moreover, pH-responsive fibers loaded with amoxicillin (AMX) were electrospun using Eudragit-EPO (EEPO), that dissolves at pH
