DETECTION AND MOLECULAR CHARACTERIZATION OF PORCINE PARVOVIRUS IN FETAL TISSUES FROM SOWS WITHOUT REPRODUCTIVE FAILURE IN ARGENTINA  

MARIA SOLEDAD SERENA; JAVIER CAPUCCIO; GERMAN ERNESTO METZ; CAROLINA ASPITIA; MARINA DIBARBORA; GALLO CALDERON, MARINA; MARIA GABRIELA ECHEVERRIA

Heliyon

Elsevier

Año: 2019

2405-8440

Porcine parvovirus (PPV) is one of many pathogens responsible for reproductive failure inpregnant sows. Several studies have reported the appearance of new PPV strains that differfrom previous isolates both genetically and antigenically. Thus, the protective effects ofcommercially inactivated vaccines could not be complete. In South America, theinformation about PPV is limited. Thus, the aim of the present study was to detect andcharacterize the PPV strains present in 131 mummies or stillbirths from normal deliveriesin sows from a commercial swine farm of Argentina that uses the commercial vaccine. PCRresults showed that 17/131 were positive to PPV. Ten of these viruses were isolated andsequenced. All viruses were related to the PPV1 sequence (NADL-2), maintaining theamino acid differences in positions 436 (S-P) and 565 (R-K). This study is the first to reportthe isolation of PPV in Argentina and the results suggest that PPV can cross the placentaeven in vaccinated sows, thus affecting some of the fetuses and being able to cause fetaldeath in sows without reproductive failure. The results also suggest that vaccination onlyreduces clinical signs and reproductive disorders and may thus not be a perfect tool tomanage PPV infection. This study provides information that needs to be studied in depth toimprove strategies to prevent and control PPV infection in swine far