INVESTIGADORES
GORLA Nora Bibiana Maria
artículos
Título:
Assessment of cytogenetic damage in chagasic children treated with benznidazole
Autor/es:
GORLA N B M; O LEDESMA; BARBIERI G; LARRIPA IRENE
Revista:
MUTATION RESEARCH
Editorial:
eLSEVIER
Referencias:
Año: 1988
ISSN:
0921-8262
Resumen:
Chromosomal aberrations and induction of micronuclei were analyzed from cultures of peripheral lymphocytes in 2 groups of chagasic children, before and after treatment with benznidazole. The median irícidence of micronucleated interphase lymphocytes (20 patients) and chromosomal aberrations (10 patients) increased from control valúes of 5/1000 and 3% to 11.5/1000 and 6%, respectively, at a significance of P = 0.05.