Hypertrophic Cardiomyopathy (HCM) in a Jaguar (Panthera onca)

MARTINO PE, ARIAS D, RODRIGUEZ R, LAPLACE R, ALONSO CR, PORTIANSKY EL AND GIMENO EJ.

REVUE DE MEDECINE VETERINAIRE

ECOLE NATIONALE VETERINAIRE TOULOUSE

Año: 2010 vol. 161 p. 16 - 19

0035-1555

A 20-month-old female jaguar (Panthera onca) developed anorexia, lethargy, loss of appetite and breathing difficulties. Echocardiography and necropsy showed a non dilated, left ventricular asymmetric myocardial hypertrophy, pulmonary oedema and pericardial and pleural effusions. Disarray of cardiac muscle cells and interstitial myocardial fibrosis were identified on histological examination. Polarized microscopy used on picrosirius red-stained sections showed an increase either of total collagen as well as of the type I/type III collagen ratio in the damaged myocardium. Clinical, gross and microscopic lesions were consistent with hypertrophic cardiomyopathy (HCM) which is for the first time described in a wild animalPanthera onca) developed anorexia, lethargy, loss of appetite and breathing difficulties. Echocardiography and necropsy showed a non dilated, left ventricular asymmetric myocardial hypertrophy, pulmonary oedema and pericardial and pleural effusions. Disarray of cardiac muscle cells and interstitial myocardial fibrosis were identified on histological examination. Polarized microscopy used on picrosirius red-stained sections showed an increase either of total collagen as well as of the type I/type III collagen ratio in the damaged myocardium. Clinical, gross and microscopic lesions were consistent with hypertrophic cardiomyopathy (HCM) which is for the first time described in a wild animal