Antimicrobial Resistance and Production of Biofilms in Clinical Isolates of Coagulase-Negatives Staphylococcus Strains.

GAUDIOSO ALLORI MC; JURE MA; ROMERO CINTIA MARIANA; CASTILLO MC

BIOL. PHARM. BULL.

Pharmaceutical Society of Japan

Año: 2006 vol. 29 p. 1592 - 1596

0918-6158

Coagulase-negative Staphylococcus (CNS) strains are frequently associated with bacteremia and hospital-acquired infections. 293 CNS strains were isolated from 744 samples from a dialysis center in S. M. de Tucumán, Argentina, from hemocultures, catheters and urine and identified as S. epidermidis, S. haemolyticus, S. saprophyticus, S. hominis and S. cohnii. 13 antibiotics were tested for antibacterial resistance. 75% of S. saprophyticus, 66% of S. epidermidis and 57% of S. haemolyticus was resistant to erythromycin and 50% of S. haemolyticus was resistant to ciprofloxacin. OXA resistance was found in 43% of S. haemolyticus. Presence of PBP 2a in OXA-R strains was confirmed with the modified agglutination assay (MRSA) and presence of the mecA gene. 15 strains with intermediate halos for vancomycin and teicoplanin showed a MIC in solid and liquid medium