PROBIOTIC ADMINISTRATION TO DOG PETS WITH GASTROENTERITIC SYMPTOMS IN A CONTROLLED, RANDOMIZED, DOUBLE BLIND TRIAL

MOLINA ROSA ALEJANDRA; MIRANDA, MARÍA HORTENCIA; MALDONADO, NATALIA C.; D'URSO VILLAR, MARCELA A.; NADER-MACIAS, MARIA ELENA F.

Mar del Plata

Congreso; REUNIÓN ANUAL DE SOCIEDADES DE BIOCIENCIA 2019; 2019

SOCIEDADES ARGENTINAS DE BIOCIENCIA

There is a renewed interest in the design of formulas containing probiotic or beneficial microorganisms for the prevention of infections and animal welfare, exerting a physiological effect (ISAPP). The objective of this work was to determine the effect of the oral administration of four strains previously selected by their beneficial properties: Lactobacillus johnsonii CRL1693, L murinus CRL1695, L mucosae CRL1696 and L salivarius CRL1702 to dog pets (from 1-4 months old) with gastrointestinal symptoms (diarrhea, fever, vomiting). The randomized, double blind placebo-controlled trial was conducted at a veterinary center in Tucumán (June 2018-July 2019) in a Treated TG (n= 60) and Placebo PG (n= 60) groups. The probiotic was administered as freeze-dried bacteria (108 CFU) or excipients for 7 days by oral route. Race, weight, sex, type of feeding and previous sickness were registered, while clinical protocols were applied for diagnostic and treatment. Fecal stools were collected for microbiological and parasitological evaluation at days 0 and 8. No significant differences were observed between the two groups at the beginning of the trial. Pets' recovery was significantly different between the groups, having an excellent score (less than 3 days) in TG, while not as good in the PG (more than 7) (Fisher, p